Glycoconjugation

GlycoForm has pioneered chemical and enzymatic manipulation of carbohydrates on proteins in a highly site and sugar selective manner affording virtually unlimited control. GlycoForm's powerful protein glycosylation and oligosaccharide synthesis technologies allow the accurate placement of complex carbohydrates at positions that are known to be critical to protein efficacy.

Glyco-SeS

GlycoForm's Glyco-SeS technology utilises the properties of selenium and sulfur compounds to ligate sugars to proteins through disulfide bonds.

Novel Synthetic Glycoprotein

The key benefits of Glyco-SeS:

  • Complete control giving single glycoforms
  • Compatible with other glycosylation methods
  • The use of fully synthetic processes allows for the introduction of novel sugars and hence novel biology
  • Proteins are expressed naked and hence can be expressed in efficient prokaryotic cell systems